Niacin is involved in the proper metabolism of fat and fat-like substances such as cholesterol. Niacin taken in a single 500mg does often causes flushing or itching. Niacin-time contains niacin prepared by a patented method to minimize these unpleasant side effects. With many people there is absolutely no flush, and the amount needed is sometimes less than needed with other forms of Niacin. Each niacin-time tablet provides a gradual release of 500mg over a period of 5 to 7 hours for sustained absorption. Supplement Facts: Serving Size: 1 Tablet Servings Per Container: 250 Amount Per Serving Niacin 500 mg Directions: Take one tablet daily at mealtime. Consult your physician before exceeding recommended use.